Used primarily as an intermediate in the synthesis of biologically active compounds, especially in pharmaceutical development. Its structure allows for selective functionalization in multi-step reactions, making it valuable in creating peptidomimetics and enzyme inhibitors. The presence of the methanesulfonate group enables efficient nucleophilic substitution, facilitating the introduction of various functional groups. Commonly employed in the preparation of protease inhibitors and receptor modulators due to its conformational rigidity and compatibility with solid-phase synthesis. Also utilized in medicinal chemistry for constructing constrained amino acid derivatives that enhance metabolic stability and binding affinity in drug candidates.