5-(Trifluoromethyl)thiophene-2-sulfonyl chloride

95%

Reagent Code: #243616
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CAS Number 954377-22-1

science Other reagents with same CAS 954377-22-1

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Weight 250.65 g/mol
Formula C₅H₂ClF₃O₂S₂
badge Registry Numbers
MDL Number MFCD27934701
inventory_2 Storage & Handling
Storage 2-8°C, Inert Gas

description Product Description

Used as a key intermediate in the synthesis of pharmaceuticals and agrochemicals, particularly in the development of bioactive molecules that require fluorinated aromatic components. Its sulfonyl chloride group readily reacts with amines and alcohols, making it valuable for constructing sulfonamides and sulfonate esters—common motifs in drug design. Frequently employed in medicinal chemistry for modifying thiophene-based scaffolds to enhance metabolic stability and lipophilicity. Also applied in the preparation of functionalized polymers and specialty materials where fluorine substitution improves thermal and oxidative resistance.

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inventory 1g
10-20 days ฿81,000.00

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5-(Trifluoromethyl)thiophene-2-sulfonyl chloride
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Used as a key intermediate in the synthesis of pharmaceuticals and agrochemicals, particularly in the development of bioactive molecules that require fluorinated aromatic components. Its sulfonyl chloride group readily reacts with amines and alcohols, making it valuable for constructing sulfonamides and sulfonate esters—common motifs in drug design. Frequently employed in medicinal chemistry for modifying thiophene-based scaffolds to enhance metabolic stability and lipophilicity. Also applied in the preparation of functionalized polymers and specialty materials where fluorine substitution improves thermal and oxidative resistance.
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