Used primarily as a key intermediate in the synthesis of selective estrogen receptor modulators (SERMs), particularly in the production of drugs for the treatment of hormone-responsive cancers such as breast cancer. It plays an essential role in constructing the core structure of next-generation antiestrogens, contributing to improved receptor binding affinity and tissue selectivity. Its benzonitrile moiety and tetrahydronaphthalene scaffold enhance metabolic stability and pharmacokinetic properties in final active pharmaceutical ingredients. Also employed in research settings for developing novel therapeutics targeting estrogen-related pathways in osteoporosis and infertility.