Used primarily as a highly reactive sulfonating agent in organic synthesis, enabling the introduction of sulfonyl fluoride groups into complex molecules. Its reactivity makes it valuable in the development of covalent inhibitors and chemical probes for biological targets. Frequently applied in medicinal chemistry for the synthesis of sulfonate esters and in the preparation of functionalized polymers. Also utilized in click chemistry applications due to the stability and reactivity of the sulfonyl fluoride moiety, supporting bioconjugation and labeling techniques.