Cyclotraxin B is primarily used in neuroscience research to study the role of TrkB receptors in the brain. It acts as a selective antagonist, inhibiting TrkB signaling, which helps researchers understand its involvement in neuroplasticity, learning, and memory processes. This compound is particularly valuable in investigating neurodegenerative diseases, such as Alzheimer's, where TrkB dysfunction is implicated. Additionally, Cyclotraxin B is utilized in experiments to explore its potential therapeutic effects in mood disorders and anxiety, as TrkB receptors are linked to the mechanisms of antidepressant drugs. Its application extends to preclinical studies aimed at developing treatments for conditions associated with altered TrkB activity.