9-Nitro-10-hydroxy camptothecin

95%

Reagent Code: #73978
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CAS Number 104267-73-4

science Other reagents with same CAS 104267-73-4

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 409.35 g/mol
Formula C₂₀H₁₅N₃O₇
inventory_2 Storage & Handling
Storage room temperature, dry

description Product Description

This compound is primarily utilized in the field of cancer research and treatment due to its potent antitumor properties. It functions as a topoisomerase I inhibitor, which means it interferes with the enzyme topoisomerase I, essential for DNA replication in cancer cells. By inhibiting this enzyme, it prevents cancer cells from dividing and growing, leading to their eventual death. It is often studied for its potential in treating various types of cancers, including colorectal, ovarian, and lung cancers. Researchers are also exploring its use in combination therapies to enhance its efficacy and reduce resistance in cancer cells. Additionally, its nitro and hydroxy groups make it a candidate for further chemical modifications to improve its pharmacokinetic properties and reduce toxicity.

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Test Parameter Specification
Purity 94.5-100
Infrared Spectrum Conforms to Structure

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Size Availability Unit Price Quantity
inventory 25mg
10-20 days ฿14,360.00

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9-Nitro-10-hydroxy camptothecin
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This compound is primarily utilized in the field of cancer research and treatment due to its potent antitumor properties. It functions as a topoisomerase I inhibitor, which means it interferes with the enzyme topoisomerase I, essential for DNA replication in cancer cells. By inhibiting this enzyme, it prevents cancer cells from dividing and growing, leading to their eventual death. It is often studied for its potential in treating various types of cancers, including colorectal, ovarian, and lung cancers.

This compound is primarily utilized in the field of cancer research and treatment due to its potent antitumor properties. It functions as a topoisomerase I inhibitor, which means it interferes with the enzyme topoisomerase I, essential for DNA replication in cancer cells. By inhibiting this enzyme, it prevents cancer cells from dividing and growing, leading to their eventual death. It is often studied for its potential in treating various types of cancers, including colorectal, ovarian, and lung cancers. Researchers are also exploring its use in combination therapies to enhance its efficacy and reduce resistance in cancer cells. Additionally, its nitro and hydroxy groups make it a candidate for further chemical modifications to improve its pharmacokinetic properties and reduce toxicity.

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