MC 1046 is primarily utilized in the field of cancer research, where it serves as a potent inhibitor of topoisomerase II, an enzyme critical for DNA replication and cell division. By targeting this enzyme, MC 1046 effectively disrupts the proliferation of cancer cells, making it a valuable tool in the study of chemotherapy mechanisms. Its application extends to preclinical studies, where it is used to evaluate the efficacy of new anticancer therapies and to understand the resistance mechanisms in various cancer types. Additionally, MC 1046 is employed in biochemical assays to investigate the role of topoisomerase II in DNA repair processes and genomic stability. Its ability to induce DNA damage and apoptosis in cancer cells also makes it a candidate for combination therapies, enhancing the effects of other chemotherapeutic agents.