Trimethyl orthoformate
99.9%
Reagent
Code: #238108
Alias
Trimethyl orthoformate; trimethoxymethane, methyl orthoformate
CAS Number
149-73-5
blur_circular Chemical Specifications
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Molecular Information
Weight
106.12 g/mol
Formula
C₄H₁₀O₃
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Registry Numbers
EC Number
205-745-7
MDL Number
MFCD00008483
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Physical Properties
Melting Point
-53 °C
Boiling Point
101-102 °C(lit.)
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Storage & Handling
Density
0.97 g/mL at 25 °C(lit.)
Storage
Room temperature, dry
description Product Description
Used as a water scavenger and protecting group reagent in organic synthesis, particularly in the formation of acetals and ketals. It helps stabilize sensitive functional groups during multi-step reactions. Commonly applied in pharmaceutical manufacturing to protect aldehyde or ketone groups. Also used in the production of agrochemicals, dyes, and fragrances due to its ability to drive condensation reactions efficiently. Acts as a methylating agent in certain reactions, offering advantages over more hazardous reagents. Its low toxicity and ease of handling make it preferred in industrial-scale processes.
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