Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of sulfonamide-based drugs. Its sulfonyl fluoride group enables selective reactions with nucleophiles, making it valuable in medicinal chemistry for building bioactive molecules. Also employed in agrochemical synthesis to create herbicides and pesticides due to its stability and reactivity. Increasingly applied in chemical biology for probe and inhibitor design, where it acts as a warhead in covalent targeting of enzymes. Its chlorine and thiophene moieties enhance binding selectivity in drug candidates.