2-(2-((tert-Butoxycarbonyl)amino)thiazol-4-yl)-2-oxoacetic acid

95%

Reagent Code: #58549
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CAS Number 73181-56-3

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 272.28 g/mol
Formula C₁₀H₁₂N₂O₅S
badge Registry Numbers
MDL Number MFCD18074182
inventory_2 Storage & Handling
Density 1.453±0.06 g/cm3(Predicted)
Storage 2-8°C

description Product Description

This compound, 2-(2-((tert-Butoxycarbonyl)amino)thiazol-4-yl)-2-oxoacetic acid, is a key protected intermediate in the pharmaceutical industry, primarily for the synthesis of third-generation cephalosporin antibiotics such as cefotaxime, ceftriaxone, and related drugs. The Boc group protects the 2-amino functionality on the thiazole ring, while the glyoxylic acid moiety enables coupling to the 7-aminocephalosporin core via amide bond formation. After coupling, the protecting group is removed to yield the active side chain essential for broad-spectrum activity against Gram-negative bacteria.

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Size Availability Unit Price Quantity
inventory 1g
10-20 days ฿3,753.00
inventory 250mg
10-20 days ฿1,395.00
inventory 5g
10-20 days ฿12,204.00

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