2-(5-Tetrazolyl)ethanamine Hydrochloride
98%
science Other reagents with same CAS 33841-57-5
blur_circular Chemical Specifications
description Product Description
Used in pharmaceutical synthesis as a key intermediate for angiotensin II receptor antagonists, particularly in the production of sartan-class drugs like losartan and valsartan. The tetrazole ring enhances binding affinity to the angiotensin receptor due to its ability to mimic the carboxylate group while offering improved metabolic stability and bioavailability. Also employed in the development of other bioactive molecules where the tetrazole moiety serves as a pharmacophore. Its amine functionality allows for further chemical modifications, making it valuable in medicinal chemistry for building complex drug structures.
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