Used as a key intermediate in the synthesis of sulfa drugs, particularly sulfonamide antibiotics. It reacts with amines to form sulfonamides, which are active against a range of bacterial infections. Also employed in the preparation of agrochemicals and dyes due to its ability to introduce sulfonyl groups into organic molecules. In research, it serves as a building block in click chemistry and protein labeling due to the reactivity of the sulfonyl fluoride group with nucleophilic amino acids. Its stability and selective reactivity make it valuable in medicinal chemistry for developing enzyme inhibitors.