Used as a key intermediate in the synthesis of pharmaceuticals, particularly in the development of protease inhibitors and other biologically active compounds. Its sulfonyl fluoride group readily reacts with nucleophiles, making it valuable in organic synthesis for introducing the difluorobenzenesulfonyl moiety. It is also employed in chemical biology as a labeling agent due to its ability to selectively modify serine and threonine residues in proteins. Additionally, it serves as a building block in the preparation of agrochemicals and functional materials where fluorinated groups enhance stability and reactivity.