2-Bromo-4-(trifluoromethyl)benzenesulfonyl chloride
97 %
Reagent
Code: #144906
CAS Number
54403-98-4
blur_circular Chemical Specifications
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Molecular Information
Weight
323.51 g/mol
Formula
C₇H₃BrClF₃O₂S
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Registry Numbers
MDL Number
MFCD03094394
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Physical Properties
Boiling Point
235-236°C (Lit.)
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Storage & Handling
Density
1.8650 g/cm3
Storage
Room temperature, dry
description Product Description
Used primarily as a key intermediate in the synthesis of agrochemicals and pharmaceuticals, particularly in the development of herbicides and fungicides. Its sulfonyl chloride group readily reacts with amines and alcohols, making it valuable for constructing sulfonamide and sulfonate ester derivatives. It is also employed in the preparation of sulfonamide-based bioactive molecules, including kinase inhibitors and other medicinal agents. Due to the electron-withdrawing trifluoromethyl and bromo substituents, it enhances reactivity in cross-coupling reactions, supporting its use in advanced organic synthesis and drug discovery.
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