3-Bromo-5-(trifluoromethyl)benzenesulfonyl chloride
97%
Reagent
Code: #144853
CAS Number
351003-46-8
blur_circular Chemical Specifications
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Molecular Information
Weight
323.51 g/mol
Formula
C₇H₃BrClF₃O₂S
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Registry Numbers
MDL Number
MFCD03094393
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Physical Properties
Boiling Point
217-218°C - (Lit.)
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Storage & Handling
Storage
2-8°C, sealed, dry
description Product Description
Used primarily as a key intermediate in the synthesis of pharmaceuticals and agrochemicals. Its structure allows for selective functionalization in drug development, particularly in the creation of sulfonamide-based compounds with biological activity. Commonly employed in the preparation of kinase inhibitors and other bioactive molecules due to the electron-withdrawing nature of the trifluoromethyl and sulfonyl groups. Also utilized in materials science for designing specialty polymers with enhanced thermal and oxidative stability. The bromine moiety enables further cross-coupling reactions, making it valuable in modular synthetic routes.
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