3-Chloro-4-(trifluoromethoxy)benzene-1-sulfonyl chloride
98%
Reagent
Code: #129538
CAS Number
886762-48-7
blur_circular Chemical Specifications
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Molecular Information
Weight
295.06 g/mol
Formula
C₇H₃Cl₂F₃O₃S
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Registry Numbers
MDL Number
MFCD04972750
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Storage & Handling
Storage
2-8°C
description Product Description
Used primarily as a key intermediate in the synthesis of pharmaceuticals and agrochemicals. Its sulfonyl chloride group enables easy formation of sulfonamides and sulfonate esters, which are common structural motifs in bioactive molecules. Particularly valuable in developing herbicides and fungicides due to the presence of the trifluoromethoxy and chloro substituents, which enhance lipophilicity and metabolic stability. Also employed in the preparation of sulfa drugs and kinase inhibitors in medicinal chemistry research. Its reactivity allows for selective derivatization, making it useful in combinatorial chemistry and high-throughput screening campaigns.
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