1-((Benzyloxy)carbonyl)azetidine-2-carboxylic acid
90%
Reagent
Code: #141161
CAS Number
174740-81-9
blur_circular Chemical Specifications
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Molecular Information
Weight
235.24 g/mol
Formula
C₁₂H₁₃NO₄
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Registry Numbers
MDL Number
MFCD10568301
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Physical Properties
Boiling Point
421.2±45.0 °C(Predicted)
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Storage & Handling
Density
1.362±0.06 g/cm3(Predicted)
Storage
Room temperature, seal, dry
description Product Description
Used as an intermediate in the synthesis of pharmaceutical compounds, particularly in the development of beta-lactam antibiotics. It serves as a protected form of azetidine-2-carboxylic acid, enabling selective reactions in peptide and heterocyclic chemistry. Its structure allows incorporation into larger molecules where the azetidine ring acts as a conformationally restricted amino acid mimic, useful in medicinal chemistry for optimizing metabolic stability and bioavailability. Commonly employed in solid-phase and solution-phase peptide synthesis due to the stability and ease of removal of the benzyloxycarbonyl (Cbz) protecting group.
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