20,21-Dehydro Spironolactone
96%
blur_circular Chemical Specifications
description Product Description
Used primarily as an active pharmaceutical ingredient in research settings, this compound serves as a key intermediate in the synthesis of steroidal agents with antimineralocorticoid and antiandrogenic properties. It is particularly valuable in the development of medications targeting hormonal disorders such as hyperaldosteronism, hypertension, and conditions related to androgen excess like hirsutism and acne. Due to its structural similarity to spironolactone, it exhibits affinity for steroid receptors, making it useful in studies exploring receptor binding and antagonism. Additionally, it has been investigated for potential use in oncology research, especially in hormone-sensitive cancers such as prostate cancer, where modulation of steroid pathways is critical. Its dehydro modification enhances metabolic stability, which can improve the efficacy and duration of action in therapeutic applications.
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