Used in pharmaceutical research as a key scaffold for developing bioactive molecules, particularly in the discovery of central nervous system (CNS) agents. Its spirocyclic structure provides three-dimensional complexity, enhancing selectivity and metabolic stability in drug candidates. Commonly explored in the development of receptor modulators, including those targeting serotonin and dopamine receptors. Also employed in medicinal chemistry for optimizing lead compounds due to its favorable pharmacokinetic properties and ability to improve solubility and binding affinity.