D-Sphingosine plays a key role in cell signaling, particularly in regulating cell growth, differentiation, and apoptosis. It acts as a bioactive lipid mediator in various cellular processes and is involved in the suppression of protein kinase C activity, which influences tumor cell proliferation. Due to its role in inducing programmed cell death, it is studied extensively in cancer research, especially in understanding mechanisms of chemotherapeutic agents. It also serves as a precursor for sphingosine-1-phosphate, another signaling molecule involved in immune response and inflammation. In dermatology, D-sphingosine is used in skincare products for its ability to support skin barrier function and antimicrobial properties, helping to maintain healthy skin and prevent infections.