Simulated gastric juice is widely used in pharmaceutical and biomedical research to evaluate the stability and dissolution behavior of oral medications under conditions that mimic the human stomach environment. It helps scientists study how drugs break down in acidic conditions and assess their bioavailability before entering the intestines. This is critical for developing formulations that can withstand stomach acid or release active ingredients at the right location. It is also used in food science to investigate the digestion of proteins and other nutrients, as well as to test the safety and breakdown of food additives, supplements, and novel ingredients. In microbiology, simulated gastric juice serves as a tool to assess the survival of pathogens or probiotics during gastric transit, supporting research on infectious diseases and gut health. Additionally, it plays a role in validating sterilization and disinfection procedures, especially for endoscopes and medical devices exposed to gastric environments, ensuring they can be effectively cleaned and reused safely.