Trimethyl(nonafluorobutyl)silane is primarily used as a surface treatment agent to impart water and oil repellency to various materials. It is commonly applied to textiles, paper, and other substrates to create a protective, hydrophobic layer that resists staining and moisture. In the electronics industry, it serves as a coating for components to enhance their resistance to environmental factors like humidity and corrosion. Additionally, it is utilized in the production of specialty coatings for glass and ceramics, providing a durable, easy-to-clean surface. Its fluorinated properties also make it suitable for use in low-surface-energy applications, such as release agents in mold manufacturing.