Ammonium thiosulfate is widely used in photography as a fixing agent. It helps to remove unexposed silver halides from photographic films and papers, ensuring the image remains stable and clear.

In agriculture, it serves as a highly effective fertilizer, particularly for crops that require readily available sulfur and nitrogen. It is often applied through irrigation systems or as a foliar spray, promoting healthy plant growth and improving yield.

Additionally, it is utilized in mining and metallurgy for the extraction of precious metals like gold and silver. It acts as a leaching agent, dissolving these metals from ores in an environmentally friendly manner compared to traditional cyanide-based methods.

In water treatment, ammonium thiosulfate is employed to neutralize chlorine in wastewater, making it safer for discharge into the environment. It is also used in some industrial cleaning processes to remove tarnish and corrosion from metal surfaces.