Used primarily in the medical field as a phosphate binder for patients with kidney disease, helping to control high phosphate levels in the blood. It also serves as a source of calcium in supplements for patients requiring phosphate control.

It is utilized in the food industry as a buffer, stabilizer, and acidity regulator, enhancing texture and shelf life in various processed foods such as sauces, dressings, and ready-to-eat meals. Its pH control properties help inhibit microbial growth.

In industrial applications, it serves as a mordant in dyeing processes and as a component in cement production to modify setting properties. Additionally, it finds use in wastewater treatment for removing phosphates and controlling odor. It can also act as an intermediate in the synthesis of other chemicals, such as acetates, or as a catalyst in certain reactions.