Used in research and development for targeted cancer therapies, particularly in studies involving signal transduction pathways linked to tumor growth. Serves as a critical reagent in immunoassays and binding studies to evaluate monoclonal antibody interactions, including those of therapeutic agents like cetuximab and panitumumab. Facilitates the development and screening of inhibitors targeting the EGFR pathway, which is overactive in many epithelial cancers. Also employed in protein-protein interaction studies due to the Fc tag, enabling easy detection and purification using standard immunological techniques.