4-(3-Chloro-4-ureidophenoxy)-7-methoxyquinoline-6-carboxamide

98%

Reagent Code: #156614
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CAS Number 417719-51-8

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 386.79 g/mol
Formula C₁₈H₁₅ClN₄O₄
badge Registry Numbers
MDL Number MFCD32182572
thermostat Physical Properties
Melting Point >223 °C(dec.)
inventory_2 Storage & Handling
Storage Room temperature, seal, dry

description Product Description

Used in pharmaceutical research as a key intermediate in the synthesis of tyrosine kinase inhibitors, particularly for targeted cancer therapies. Shows potential in inhibiting epidermal growth factor receptor (EGFR) pathways, making it relevant in the development of treatments for non-small cell lung cancer and other solid tumors. Its structure supports high binding affinity to mutant forms of EGFR, including T790M and C797S, which are associated with resistance to earlier generations of inhibitors. Also employed in structure-activity relationship (SAR) studies to optimize potency, selectivity, and pharmacokinetic properties of novel anticancer agents.

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Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿7,930.00

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