Used as a key intermediate in the synthesis of pharmaceutical compounds, particularly in the development of kinase inhibitors for cancer treatment. Its halogen substitution pattern allows for selective cross-coupling reactions, enabling the construction of complex quinazoline-based molecules with biological activity. Commonly employed in medicinal chemistry research to optimize drug candidates targeting epidermal growth factor receptor (EGFR) and other tyrosine kinase pathways. Also utilized in the preparation of fluorescent probes and labeled compounds for biochemical assays due to the presence of multiple halogens that can be selectively displaced.