tert-butyl (3R,4R)-3-(aminomethyl)-4-hydroxypyrrolidine-1-carboxylate
97%
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description Product Description
Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of antiviral and antidiabetic drugs. Its chiral (3R,4R) structure features a free aminomethyl group at C3 and a free hydroxyl group at C4, with the pyrrolidine nitrogen protected as a tert-butyl carbamate (Boc), making it valuable in asymmetric synthesis and enabling precise construction of complex molecules. Commonly employed in the preparation of protease inhibitors and kinase inhibitors due to its ability to mimic peptide motifs and enhance metabolic stability. The Boc protection allows for selective deprotection under mild conditions, facilitating stepwise synthesis in multi-step drug manufacturing processes.
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