tert-butyl (3R,4R)-3-(aminomethyl)-4-hydroxypyrrolidine-1-carboxylate

97%

Reagent Code: #228712
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CAS Number 1002108-56-6

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 216.28 g/mol
Formula C₁₀H₂₀N₂O₃
badge Registry Numbers
MDL Number MFCD28396522
thermostat Physical Properties
Boiling Point 329.4±27.0 °C(Predicted)
inventory_2 Storage & Handling
Density 1.146±0.06 g/cm3(Predicted)
Storage 2-8°C

description Product Description

Used as a key intermediate in the synthesis of pharmaceutical agents, particularly in the development of antiviral and antidiabetic drugs. Its chiral (3R,4R) structure features a free aminomethyl group at C3 and a free hydroxyl group at C4, with the pyrrolidine nitrogen protected as a tert-butyl carbamate (Boc), making it valuable in asymmetric synthesis and enabling precise construction of complex molecules. Commonly employed in the preparation of protease inhibitors and kinase inhibitors due to its ability to mimic peptide motifs and enhance metabolic stability. The Boc protection allows for selective deprotection under mild conditions, facilitating stepwise synthesis in multi-step drug manufacturing processes.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 100mg
10-20 days ฿16,040.00
inventory 500mg
10-20 days ฿42,690.00

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