N-(5-((Diphenylphosphoryl)methyl)-4-(4-fluorophenyl)-6-isopropylpyrimidin-2-yl)-N-methylmethanesulfonamide

97%

Reagent Code: #51400
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CAS Number 289042-10-0

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 537.59 g/mol
Formula C₂₈H₂₉FN₃O₃PS
badge Registry Numbers
MDL Number MFCD09839448
thermostat Physical Properties
Boiling Point 679.125°C at 760 mmHg
inventory_2 Storage & Handling
Storage room temperature, stored under inert gas

description Product Description

This compound is primarily utilized in the field of medicinal chemistry as a key intermediate in the synthesis of biologically active molecules. It features a pyrimidine core with a diphenylphosphoryl methyl group at position 5, a 4-fluorophenyl at position 4, an isopropyl at position 6, and an N-methylmethanesulfonamide at position 2. It is often employed in the development of kinase inhibitors, which are crucial in targeted cancer therapies. The diphenylphosphoryl group enhances binding affinity to specific enzyme targets, while the sulfonamide moiety facilitates hydrogen bonding and interactions with biological targets, making it valuable in drug discovery processes. Additionally, structural features such as the fluorophenyl and isopropyl groups contribute to optimizing pharmacokinetic properties, including solubility and metabolic stability. Researchers also explore its application in designing compounds for neurodegenerative diseases due to its ability to modulate protein interactions, as well as potential uses in anti-inflammatory or antimicrobial agents. Its versatility makes it a significant component in the creation of novel therapeutic agents.

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿324.00
inventory 1g
10-20 days ฿792.00
inventory 10g
10-20 days ฿4,059.00
inventory 5g
10-20 days ฿2,403.00

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