Methyl 2-iodoisonicotinate is primarily used as an intermediate in organic synthesis, particularly in the pharmaceutical industry. It plays a key role in the development of various bioactive compounds and drug candidates. Its iodine substituent makes it a valuable building block for cross-coupling reactions, such as Suzuki or Sonogashira couplings, which are essential for creating complex molecular structures. Additionally, it is utilized in the synthesis of heterocyclic compounds, which are often explored for their potential therapeutic properties. Its ester group also allows for further functionalization, making it versatile in medicinal chemistry research.