3-Bromo-2-fluoro-6-iodopyridine
97%
Reagent
Code: #151864
CAS Number
1260665-99-3
blur_circular Chemical Specifications
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Molecular Information
Weight
301.88 g/mol
Formula
C₅H₂BrFIN
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Registry Numbers
MDL Number
MFCD18250719
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Storage & Handling
Storage
2-8°C, dry, light-proof
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals and agrochemicals, particularly in the development of kinase inhibitors and other biologically active compounds. Its halogen substituents allow for selective cross-coupling reactions, such as Suzuki or Buchwald-Hartwig aminations, enabling the construction of complex pyridine-based structures. Commonly employed in medicinal chemistry for lead optimization due to the ability to fine-tune electronic and steric properties. Also utilized in the preparation of fluorescent probes and functional materials where halogenated pyridines serve as building blocks.
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