Used as a key intermediate in the synthesis of pharmaceuticals and agrochemicals, particularly in the development of nicotinic receptor modulators and kinase inhibitors. The bromine substituent at the 3-position of the pyridine ring facilitates selective palladium-catalyzed cross-coupling reactions, such as Suzuki or Heck couplings, for C-C bond formation. Meanwhile, the bromomethyl group at the 5-position is amenable to nucleophilic substitution reactions, enabling the attachment of various functional groups. This orthogonal reactivity of the dual halogens makes it valuable for constructing complex pyridine-based bioactive compounds and functionalized ligands in medicinal chemistry research.