7-Hydroxypyrazolo[4,3-d]pyrimidine
97%
Reagent
Code: #194720
CAS Number
13877-55-9
blur_circular Chemical Specifications
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Molecular Information
Weight
136.11 g/mol
Formula
C₅H₄N₄O
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Storage & Handling
Storage
Room temperature, dry
description Product Description
Used as a key intermediate in the synthesis of phosphodiesterase-5 (PDE-5) inhibitors, particularly in the production of drugs for erectile dysfunction and pulmonary arterial hypertension. Its structure serves as a core scaffold in developing potent and selective inhibitors that enhance cyclic nucleotide signaling. Also explored in the development of kinase inhibitors for potential anticancer agents due to its ability to mimic purine bases in enzyme active sites. Commonly employed in medicinal chemistry for structure-activity relationship (SAR) studies targeting central nervous system disorders and inflammation.
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