4-Iodo-1-methyl-1H-pyrazole
97%
Reagent
Code: #199265
Alias
4-iodo-1-methyl-1H-pyrazole; 1-methyl-4-iodo-pyrazole
CAS Number
39806-90-1
blur_circular Chemical Specifications
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Molecular Information
Weight
208 g/mol
Formula
C₄H₅IN₂
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Registry Numbers
MDL Number
MFCD05663860
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Physical Properties
Melting Point
61-67 °C
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Storage & Handling
Storage
2~8°C
description Product Description
Used as a key intermediate in the synthesis of pharmaceuticals and agrochemicals, particularly in the development of bioactive molecules that require halogenated heterocyclic cores. Its iodine functionality allows for further transformations via cross-coupling reactions such as Suzuki or Heck reactions, enabling the construction of complex organic structures. Commonly employed in medicinal chemistry for lead optimization due to the favorable steric and electronic properties of the methylpyrazole scaffold. Also utilized in the preparation of kinase inhibitors and other targeted therapies in drug discovery programs.
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