2-Amino-5-phenylpyrazine is primarily used in the field of organic synthesis and pharmaceutical research. It serves as a key intermediate in the development of various bioactive compounds, particularly in the synthesis of heterocyclic molecules. These molecules are often explored for their potential therapeutic applications, including antimicrobial, anticancer, and anti-inflammatory properties. Additionally, its structure makes it a valuable building block in the design of ligands for metal coordination chemistry, which is useful in catalysis and material science. The compound is also studied in the context of drug discovery for its potential to modulate biological targets and pathways.