This compound is primarily used in peptide synthesis as a protected form of serine. The Boc (tert-butoxycarbonyl) group serves as a protective group for the amino group, while the O-methyl group protects the hydroxyl group on the serine side chain. The carboxylic acid remains free, enabling coupling reactions during synthesis. This protection strategy allows for selective reactions at other sites of the peptide chain, preventing unwanted side reactions involving the hydroxyl group. It is particularly useful in solid-phase peptide synthesis (SPPS) and solution-phase methods, aiding in the construction of complex peptides. After incorporation, the Boc group can be deprotected under acidic conditions, while the O-methyl group provides permanent protection for the side chain in many applications. Its use is essential in producing pharmaceuticals, research peptides, and biologically active compounds.