This compound, Fmoc-N-methylglycine hydrate (also known as Fmoc-Sar-OH hydrate), serves as a specialized building block in solid-phase peptide synthesis (SPPS). The fluorenylmethoxycarbonyl (Fmoc) group protects the nitrogen of N-methylglycine (sarcosine), offering stability in basic conditions and easy removal under mild acidic conditions. This prevents unwanted side reactions, facilitating precise peptide chain assembly. Its broad compatibility with solvents and reagents positions it as a vital intermediate for synthesizing complex peptides and proteins in pharmaceutical and biochemical applications. The hydrate form improves stability, solubility, and ease of handling in lab settings.