Boc-Orn(Fmoc)-OH is widely used in peptide synthesis as a building block for creating complex peptide structures. Its dual protection with Boc (tert-butyloxycarbonyl) and Fmoc (fluorenylmethyloxycarbonyl) groups allows for selective deprotection and sequential assembly of peptides. This compound is particularly valuable in solid-phase peptide synthesis (SPPS), where it helps introduce ornithine residues into peptide chains with high precision. It is also employed in the development of peptide-based drugs, biomaterials, and research tools, enabling the study of peptide interactions and functions. The orthogonal protection strategy ensures efficient and controlled synthesis, making it a key reagent in both academic and industrial peptide chemistry.