Boc-Ser(Ala-Fmoc)-OH
98%
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description Product Description
This chemical is a specialized building block in peptide synthesis, specifically N-Boc-O-(N-Fmoc-L-alanyl)-L-serine. The Boc (tert-butyloxycarbonyl) group protects the α-amine of serine, while the side chain hydroxyl of serine is protected via an ester linkage to N-Fmoc-alanine. This dual protection strategy, incorporating an Fmoc-protected alanine residue on the serine side chain, enables selective deprotection and orthogonal protection schemes during stepwise peptide assembly. It is essential in solid-phase peptide synthesis (SPPS) for constructing complex peptides with precise sequence control and high purity. Applications include pharmaceutical research, biotechnology, and the development of therapeutic peptides and peptidomimetics.
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