(S)-5-((9H-Fluoren-9-yl)methoxy)-4-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-5-oxopentanoic acid

97%

Reagent Code: #60738
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CAS Number 200616-18-8

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 547.60 g/mol
Formula C₃₄H₂₉NO₆
badge Registry Numbers
MDL Number MFCD00237656
inventory_2 Storage & Handling
Storage 2-8°C

description Product Description

This compound is the Fmoc-protected derivative of L-glutamic acid, specifically (S)-Fmoc-Glu(Fmoc)-OH, where the α-amino group is protected with a fluorenylmethoxycarbonyl (Fmoc) group and the side-chain γ-carboxylic acid is protected as an Fmoc ester. It serves as a key building block in solid-phase peptide synthesis (SPPS) for incorporating glutamic acid residues into peptide chains. The Fmoc protections prevent unwanted side reactions: the α-Fmoc shields the amine functionality to enable controlled, stepwise peptide assembly, while the side-chain Fmoc ester protects the carboxylic acid. Both Fmoc groups are orthogonally removable under mild basic conditions (e.g., using piperidine in DMF), making this compound highly suitable for efficient SPPS. It is particularly valuable in producing complex peptides and proteins for pharmaceutical research, drug development, and biochemical studies, ensuring high purity and precision in synthesizing biologically active molecules.

format_list_bulleted Product Specification

Test Parameter Specification
Appearance solid
Purity 96.5-100
Infrared Spectrum Conforms to Structure
NMR Conforms to Structure

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Size Availability Unit Price Quantity
inventory 250mg
10-20 days ฿2,240.00

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