Boc-N-Me-Arg(Mtr)-OH
98%
Reagent
Code: #59166
CAS Number
125602-26-8
blur_circular Chemical Specifications
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Molecular Information
Weight
500.62 g/mol
Formula
C₂₂H₃₆N₄O₇S
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Registry Numbers
MDL Number
MFCD00236863
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Storage & Handling
Storage
Room temperature, sealed, dry
description Product Description
This chemical is primarily used in peptide synthesis as a protected N-methylamino acid derivative, specifically for incorporating N-methylarginine. It serves as a building block for constructing peptides, particularly in solid-phase peptide synthesis (SPPS). The Boc (tert-butoxycarbonyl) group protects the N-methylamino group, while the Mtr (4-methoxy-2,3,6-trimethylbenzenesulfonyl) group safeguards the guanidine function of the arginine side chain. This protection ensures selective reactions during peptide chain assembly, preventing unwanted side reactions. It is especially useful in synthesizing peptides containing N-methylarginine residues, which are common in biologically active peptides and proteins. After peptide synthesis, the protecting groups can be removed under specific conditions to yield the desired peptide sequence. Its application is critical in pharmaceutical research, drug development, and the study of protein-protein interactions.
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