The methylamide of N-t-butyloxycarbonyl-L-methionine (Boc-Met-NHCH₃) is a protected amino acid derivative primarily used in peptide synthesis. The t-butyloxycarbonyl (Boc) group protects the α-amino group of the L-methionine residue, preventing unwanted side reactions during peptide bond formation. The methylamide functionality at the carboxyl terminus enables its use as a C-terminal building block, particularly in solid-phase peptide synthesis (SPPS), for constructing peptides that terminate with a methionine methylamide. This compound is essential for achieving high-purity peptides in the development of peptide-based pharmaceuticals and biochemical research, where precise control over amino acid reactivity is required. Its stability under various reaction conditions makes it a reliable choice for complex peptide assembly.