Fmoc-(3-aminomethyl) benzoic acid
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Fmoc-(3-aminomethyl) benzoic acid is widely used in peptide synthesis as a protecting group for amines. It is particularly valuable in solid-phase peptide synthesis (SPPS), where the Fmoc group ensures selective protection of the amino group during the coupling process. This compound allows for the controlled elongation of peptide chains, as the Fmoc group can be easily removed under mild basic conditions, such as using piperidine, without affecting other functional groups. Additionally, its benzoic acid moiety provides versatility in linking to resins or other molecules, making it a crucial building block in the development of peptides for pharmaceutical research and drug discovery. Its stability and compatibility with various synthetic protocols further enhance its utility in organic and medicinal chemistry.
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