(2S,4S)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-4-hydroxypyrrolidine-2-carboxylic acid
98%
Reagent
Code: #235032
CAS Number
189249-10-3
blur_circular Chemical Specifications
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Molecular Information
Weight
353.37 g/mol
Formula
C₂₀H₁₉NO₅
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Storage & Handling
Storage
2-8°C
description Product Description
Widely used in peptide synthesis and medicinal chemistry, this compound serves as a chiral building block for the preparation of complex organic molecules, particularly those requiring stereochemical control. Its hydroxyl and carboxylic acid functionalities allow for selective derivatization, making it valuable in the development of protease inhibitors and other biologically active compounds. The Fmoc-protected amine group enables compatibility with solid-phase peptide synthesis (SPPS), where it can be incorporated into peptide chains under mild basic conditions. It is especially useful in the synthesis of collagen mimetics and proline analogs due to its pyrrolidine backbone. Additionally, the presence of the hydroxy group offers a handle for further modification, such as glycosylation or phosphorylation, in the design of glycopeptides or enzyme substrates.
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