Used in solid-phase peptide synthesis as a protected amino acid building block, particularly for incorporating non-natural phenyl-substituted alanine derivatives into peptide chains. The Fmoc group allows for mild base deprotection, compatible with a wide range of side-chain protecting groups. Its 2,3-dimethoxyphenyl moiety can influence peptide conformation and enhance binding selectivity in bioactive peptides, making it valuable in drug discovery and development of peptidomimetics. Commonly applied in the synthesis of receptor ligands and enzyme inhibitors where aromatic side chains modulate biological activity.