Ac-PHG-OMe is primarily used in peptide synthesis and biochemical research. It serves as a building block for creating more complex peptide structures, often utilized in the study of peptide interactions and enzyme mechanisms. Its modified structure makes it valuable for stabilizing peptides and enhancing their bioavailability in experimental settings. Additionally, it is employed in the development of peptide-based drugs and therapeutic agents, particularly in targeting specific biological pathways. Its application extends to the field of proteomics, where it aids in the analysis of protein functions and interactions.