Z-D-Trp-OMe is primarily used in peptide synthesis as a building block for constructing complex peptide chains. It serves as a protected form of tryptophan, ensuring the amino acid remains stable during the synthesis process. This compound is particularly valuable in research applications where specific peptide sequences are required for studying biological interactions, enzyme functions, or developing therapeutic agents. Its use allows for precise control over peptide structure, which is critical in drug discovery and biochemical studies. Additionally, Z-D-Trp-OMe is employed in the development of peptidomimetics, which are molecules designed to mimic the structure and function of natural peptides, often with enhanced stability or activity.