Boc-L-serine benzyl ester is widely used in peptide synthesis as a protected form of serine. The Boc (tert-butoxycarbonyl) group safeguards the amino group, while the benzyl ester protects the carboxyl group, allowing selective reactions during peptide chain assembly. It is particularly valuable in solid-phase peptide synthesis (SPPS), where controlled deprotection and coupling steps are essential. This compound is also employed in the preparation of serine-containing peptides for pharmaceutical research, enabling the development of drug candidates, enzyme inhibitors, and bioactive peptides. Its stability and ease of removal under specific conditions make it a preferred choice in organic and medicinal chemistry.