N-Cbz-L-4-Hydroxyproline methyl ester

95%

Reagent Code: #105437
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Alias N-CBZ-Hydroxyproline methyl ester
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CAS Number 64187-48-0

blur_circular Chemical Specifications

scatter_plot Molecular Information
Weight 279.29 g/mol
Formula C₁₄H₁₇NO₅
badge Registry Numbers
MDL Number MFCD00055851
inventory_2 Storage & Handling
Density 1.313
Storage -20°C

description Product Description

Used in peptide synthesis as a protected amino acid derivative, it helps in the construction of complex peptides by providing stability to the hydroxyproline residue during reactions. It is particularly valuable in the production of collagen-like peptides and other bioactive molecules where hydroxyproline plays a critical role. The N-Cbz protecting group ensures selective deprotection, allowing for controlled and efficient synthesis. Additionally, it is employed in the development of pharmaceuticals targeting connective tissue disorders and wound healing due to its structural similarity to natural collagen components. Its methyl ester form enhances solubility, making it easier to handle in organic solvents during synthesis.

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Test Parameter Specification
Carbon (By Elemental Analysis) 43.9-45.2
Nitrogen 4.4-5.1
Purity (HPLC) 95-100%
Specific Rotation (23 Degree Celsius, 589 Nm) (c=0.1, H2o)
Proton NMR Spectrum Conforms To Structure
Solubility Clear colorless solution (50 mg/ml, water)
Appearance Light yellow liquid
Appearance Light yellow liquid

shopping_cart Available Sizes & Pricing

Size Availability Unit Price Quantity
inventory 5g
10-20 days ฿360.00
inventory 25g
10-20 days ฿1,260.00
inventory 100g
10-20 days ฿3,950.00
inventory 500g
10-20 days ฿14,193.00

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