1-Fmoc-piperidine-4-carboxylic acid is employed in peptide synthesis as a protected building block, where the Fmoc group safeguards the piperidine nitrogen (secondary amine), enabling selective coupling of the carboxylic acid to the growing peptide chain. It is especially useful in solid-phase peptide synthesis (SPPS) due to the Fmoc group's stability under acidic conditions and facile removal with mild bases like piperidine. This allows precise control over peptide assembly and incorporation of the piperidine-4-carboxylic acid moiety into complex structures. The compound also finds applications in synthesizing pharmaceutical intermediates, bioactive molecules, peptidomimetics, and other organic compounds that benefit from selective amine protection.